Brainware Safari, winner of the Parents' Choice Award in 2006, that I use in vision therapy. We do the drill working on spatial orientation: Is the triangle above/below and to the left/right of the box. Also,we work on visual memory by copying the abstract figure. It's a lot of fun. Pick your safari animal and away you go!
Here's some of the research behind it at SharpBrains. The article at SharpBrains also debunks some of the hype surrounding brain fitness games. And here's a book about brain fitness games that also looks at Brainware Safari written by some leading neuroscientists.