Wednesday, May 18, 2011

Smell, Memory and My Big Fat Honkingly Large Neuron

A single interneuron controls activity adaptively in 50,000 neurons, enabling consistently sparse codes for odors. 
The brain is a coding machine: it translates physical inputs from the world into visual, olfactory, auditory, tactile perceptions via the mysterious language of its and the networks which they form. Neural codes could in principle take many forms, but in regions forming bottlenecks for information flow (e.g., the ) or in areas important for memory, sparse codes are highly desirable. Scientists at the Max Planck Institute for Brain Research in Frankfurt have now discovered a single neuron in the brain of that enables the adaptive regulation of sparseness in olfactory codes. This single giant interneuron tracks in real time the activity of several tens of thousands of neurons in an olfactory centre and feeds inhibition back onto all of them, so as to maintain their collective output within an appropriately sparse regime. In this way, representation sparseness remains steady as input intensity or complexity varies.

A giant interneuron for sparse coding

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